*** UPDATE: Rollup 9 FIXES THIS ISSUE, PLEASE UPGRADE TO UR9 ***
Today in the building i had someone ask me about this issue, now i had this issue myself for sometime and thought it was just my machine, well i am a developer and you know how we love to cause issues for ourselves.
now as your aware menus in CRM can have sub-menu items such as shown in the image below

BUT, for some reason mine and my colleagues menus were like this:

Now as you can see the sub-menu has overlaid itself on the root menu, now if i was trying to get to the “Send Shortcut” Node i couldn’t., now some menus this is still possible to get to such as:

So the Journey had begin to find the solution, alas Google didn’t turn up anything except others with the same issue
Now all i knew was this is due to some IE8 setting as it seemed to work fine in the IE7 clients.
so i started off by resetting my browser settings to default, reloaded CRM and hey presto it worked!, Now being a developer was not satisfied with that solution, so the first thing was to add the CRM site back to the “Trusted Sites” list and BANG.. problem appeared again.
So now i new it must be something in the Zone settings of IE8, so painfully went through each setting until the problem disappeared.
“YER GET ON WITH IT” i hear you say.
well the setting is “Allow script-initiated windows without size or position constraints” was set to Disable.
Enable this Setting and the issue disappears, Now i have to say at this point am at a loss, because as with most applications there is a lot of settings but NO HELP as to what they do or impact…
jeez, since when have we started buying products without comprehensive manuals?
Anyway rant over, problem fixed and on to the next one.